Vitamin C-mechanisms of action and use in cancer.

General information only.

The use of high-dose intravenous vitamin C (HDIVC) as a principal therapy in cancer care.

Mechanisms of Action

Vitamin C acts as a major water-soluble antioxidant at physiological concentrations but can generate hydrogen peroxide at higher concentrations. At high concentrations, vitamin C can act as a pro-oxidant, generating hydrogen peroxide, which is s…